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MK-677 is a first-in-class ghrelin mimetic that increases both GH and IGF-1 levels without altering cortisol or testosterone, offering anabolic potential with minimal endocrine disruption. Murphy et al., Nature Reviews Drug Discovery How Does MK-677 Work

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The mental health dimension also warrants clinical attention: a significant proportion of peptide use, particularly within the gym and bodybuilding community, is driven by body dysmorphic concerns rather than genuine health optimization goals, and Brooke Bowmans case is a reminder that for some users, the compulsive self-experimentation is performing functions that addiction previously served